Case 56: Udderly Blinded: A Case of Chronic Ocular Trauma Unmasked by POCUS

Martin Day, Elaine Yu

A 69-year-old male with no significant past medical history presented to the emergency department after striking his right eye with the handle of a spray hose at work. He reported burning pain but denied bleeding, tearing, or other injuries. Eye movement did not exacerbate the pain. Notably, he had been chronically blind in the right eye since childhood after sustaining blunt ocular trauma from being kicked by a cow around age 12. He described no perception of light in that eye since then.

Vitals: BP 138/83 | Pulse 85 | Temp 98.4F (36.9C) | Resp 17 | SpO2 98%

Physical Exam:

On physical examination, the patient was alert and cooperative, not in acute distress. The right eye did not demonstrate periorbital ecchymosis or signs of obvious trauma. There was negative fluorescein uptake, extraocular movements intact, and pupil fixed. He had no light perception. His left eye was normal on examination.

A bedside ocular ultrasound was performed:

Figure 1. Bi-convex lens with hyperechoic but irregular borders.

Figure 2. Ocular ultrasound depicting hyperechoic debris within the posterior chamber and vitreous hemorrhage, represented as materials of varying echogenicity within the vitreous body.

ED Course

Pain was treated conservatively with topical anesthetics and fluorescein for exam. Patient did not require any acute intervention. He was reassured, educated on return precautions, and discharged in stable condition.

Discussion

Blunt ocular trauma can cause profound and often irreversible injury. In this patient, a cow kick to the eye at age 12 resulted in permanent blindness. Decades later, a new minor injury prompted re-evaluation, but his underlying chronic pathology was the dominant finding.

Despite an apparently benign surface exam—negative fluorescein, intact EOMI, no external trauma—ultrasound revealed chronic posterior segment pathology: vitreous detachment, hemorrhage, and irregular lens, consistent with his long-standing blindness. Notably, POCUS excluded emergent findings such as global rupture or retinal detachment.

The American College of Emergency Physicians recommends POCUS for assessing the posterior segment of the eye. Multicenter trials and meta-analyses convey high sensitivity and specificity for retinal detachment (96.9% sensitivity, 88.1% specificity), moderate diagnostic accuracy for vitreous hemorrhage (81.6% sensitivity, 82.3% specificity), and lower sensitivity (42.5%) but high specificity (96.0%) for vitreous detachment [1,2,3,5]. Additionally, POCUS was 100% sensitive and 97% specific for lens dislocation, and 100% sensitive and 99% specific for intraocular foreign body according to another meta-analysis [1,5].

Vitreous hemorrhage appears on ocular ultrasound as a fluid collection of variable echogenicity within the posterior chamber of the globe. The hemorrhagic material typically is mobile, shifting as the patient moves their eye while the probe remains still [2]. In chronic cases, fibrotic changes may cause the echogenic fluid collection to appear denser and more organized [1,2]. Vitreous detachment appears as a mobile, hyperechoic membrane in the posterior chamber, like vitreous hemorrhage, during kinetic examination [3]. Retinal detachment can be differentiated from vitreous detachment because it appears more echoic and anchored to the optic disc, which was not appreciated in this case [2,3]. The lens on ocular ultrasound may appear irregular in its position or contour [3]. This patient’s lens appeared typically centered behind the iris without evidence of dislocation. However, the margins were poorly defined, with irregular, asymmetric borders, suggestive of a lens irregularity [3,6].

In emergency medicine, ocular ultrasound offers a quick and effective means of evaluating both acute injuries and chronic sequelae. This case highlights the value of ultrasound in diagnosing both acute and chronic ocular pathology. It allows rapid, non-invasive assessment of posterior structures even when vision is absent or the anterior exam appears normal. A visit to the ED for a minor workplace incident uncovered sequela of a childhood injury. Additionally, clinical judgment helped guide diagnosis. With no suspicion of intraocular foreign body or orbital fracture, CT was deemed unnecessary. Ultrasound was sufficient to distinguish chronic from acute findings.  POCUS may be especially useful for assessing unreliable historians. POCUS does not replace the comprehensive ophthalmologic evaluation [4]. Nonetheless, it serves as a crucial tool for rapid bedside assessment for urgent intervention [4].

References

  1. American College of Emergency Physicians. Ultrasound Guidelines: Emergency, Point-of-Care, and Clinical Ultrasound Guidelines in Medicine. Irving, TX: American College of Emergency Physicians; 2023.
  2. Lahham S, Shniter I, Thompson M, et al. Point-of-care ultrasonography in the diagnosis of retinal detachment, vitreous hemorrhage, and vitreous detachment in the emergency department. JAMA Netw Open. 2019;2(4):e192162. doi:10.1001/jamanetworkopen.2019.2162
  3. Pyle M, Gallerani C, Weston C, Frasure SE, Pourmand A. Point of care ultrasound and ocular injuries: a case of lens dislocation and a comprehensive review of the literature. J Clin Ultrasound. 2021;49(3):282-285. doi:10.1002/jcu.22904
  4. Blaivas M, Theodoro D, Sierzenski PR. A study of bedside ocular ultrasonography in the emergency department. Acad Emerg Med. 2002;9(8):791-799. doi:10.1111/j.1553-2712.2002.tb02166.x
  5. Propst SL, Kirschner JM, Strachan CC, et al. Ocular point-of-care ultrasonography to diagnose posterior chamber abnormalities: a systematic review and meta-analysis. JAMA Netw Open. 2020;3(2):e1921460. doi:10.1001/jamanetworkopen.2019.21460
  6. Özdal M, Mansour M, Deschênes J. Ultrasound biomicroscopic evaluation of the traumatized eyes. Eye (Lond). 2003;17(4):467-472. doi:10.1038/sj.eye.6700382

Case 55: Diagnosing Posterior Ocular Chamber Abnormalities with Point-of-Care Ultrasound

Kevin Vo, MD; Rachna Subramony, MD

Case Presentation:
A 31-year-old male with no significant past medical history presented to the Emergency Department with bilateral blurry vision, left greater than right. He had been evaluated earlier that day by an optometrist and referred for concern of retinal detachment. The patient reported flashes and floaters of uncertain duration but denied eye pain, discharge, foreign body sensation, headache, or trauma.

Vital Signs: BP 132/77 mmHg | HR 60 bpm | Temp 97.3°F | RR 16 | SpO₂ 99%

Physical Examination:
The patient was in no acute distress. Ocular exam revealed mild conjunctival injection bilaterally. Intraocular pressures were 17 mmHg OS and 13 mmHg OD. Fluorescein exam showed no corneal uptake. Neurologic exam was normal; the patient was alert and oriented ×3 without focal deficits. The patient reported a superior visual field deficit in the left eye.

A bedside ultrasound was performed.

Figure 1 (video) : Echogenic detached membrane visualized in the posterior chamber of the left eye

Figure 2 (video): Detachment tethered to the optic nerve.

Discussion: 

Point-of-care ultrasound (POCUS) is a valuable adjunct for emergency physicians in evaluating posterior ocular abnormalities. While anterior and external ocular conditions can often be diagnosed through history and physical examination, posterior chamber visualization is frequently limited in the emergency department due to the lack of specialized ophthalmic equipment and suboptimal exam conditions.

POCUS offers a noninvasive, rapid, and radiation-free imaging modality that can enhance diagnostic accuracy in the acute care setting. Meta-analyses and prospective studies have demonstrated POCUS sensitivity of 94–97% and specificity of 88–96% for detecting retinal detachment1,2,3. Given this high sensitivity, POCUS can serve as an effective rule-out tool when used in conjunction with ophthalmologic evaluation.

Retinal detachment typically appears as an echogenic, undulating membrane tethered to the optic nerve, a finding considered diagnostic in multiple studies.1,5 In this case, the optic nerve was difficult to visualize in the same plane as the detached membrane, making it challenging to definitively distinguish retinal from posterior vitreous detachment (Figure 2). However, given the patient’s corresponding visual field deficits and characteristic sonographic findings, the likelihood of retinal detachment remained high.

The use of POCUS for diagnosing vitreous detachment differs from its performance for retinal detachment. In one prospective study, sensitivity and specificity were 42.5% and 96% respectively.3 Another meta-analysis showed POCUS’s sensitivity to be 67% and specificity to be 90%. For other posterior eye pathologies, such as lens dislocation, foreign body, and globe rupture, sensitivity and specificity were high.1 The application of POCUS in this case was more suited for determining the presence of a retinal detachment and guiding the subsequent steps in management and further ophthalmologic assessment. The presence of vitreous detachment is difficult to rule out with the use of ultrasound alone. 

Conclusion:
This case demonstrates POCUS’s utility as an adjunct to ophthalmologic examination in the evaluation of posterior ocular pathology. Retinal detachment, which typically requires more urgent intervention than posterior vitreous detachment, can be rapidly identified using POCUS in the emergency setting. In this case, ophthalmology was consulted, and the patient subsequently underwent a left eye vitrectomy with perfluoro-octane (PFO) tamponade for treatment of his retinal detachment.

References: 

1.Propst SL, Kirschner JM, Strachan CC, et al. Ocular Point-of-Care Ultrasonography to Diagnose Posterior Chamber Abnormalities. JAMA Network Open. 2020;3(2):e1921460. doi:https://doi.org/10.1001/jamanetworkopen.2019.21460 

2.Gottlieb M, Holladay D, Peksa GD. Point‐of‐Care Ocular Ultrasound for the Diagnosis of Retinal Detachment: A Systematic Review and Meta‐Analysis. Carpenter CR, ed. Academic Emergency Medicine. 2019;26(8):931-939. doi:https://doi.org/10.1111/acem.13682 

3.Lahham S, Shniter I, Thompson M, et al. Point-of-Care Ultrasonography in the Diagnosis of Retinal Detachment, Vitreous Hemorrhage, and Vitreous Detachment in the Emergency Department. JAMA Network Open. 2019;2(4). doi:https://doi.org/10.1001/jamanetworkopen.2019.2162 

4.Ocular Ultrasound Made Easy: Step-By-Step Guide - POCUS 101. POCUS 101. Published 2018. Accessed August 4, 2025. https://www.pocus101.com/ocular-ultrasound-made-easy-step-by-step-guide/#Posterior_Vitreou s_Detachment_PVD 

5.Kim DJ, Francispragasam M, Docherty G, et al. Test Characteristics of Point‐of‐care Ultrasound for the Diagnosis of Retinal Detachment in the Emergency Department. Theodoro DL, ed. Academic Emergency Medicine. Published online December 17, 2018. doi:https://doi.org/10.1111/acem.13454

Case 54: Point-of-Care Ultrasound in Polycystic Kidney Disease with Hepatic Involvement

EJ Curtis, Colleen Sweeney, Colleen Campbell

A 70-year-old man with a past medical history of hypertension, obstructive hypertrophic cardiomyopathy, atrial fibrillation status-post Watchman procedure, and end-stage renal disease secondary to polycystic kidney disease (status-post renal transplant in 2014, complicated by chronic kidney disease stage 5 of the transplanted kidney) was brought to the emergency department after being found on the floor by his daughter. On arrival, the patient had generalized weakness, lightheadedness, and epigastric pain.

Vital signs: BP: 77/60 mmHg | HR: 103 | RR: 20 | T 37.3C

On physical exam, the patient appeared chronically ill and had scattered ecchymoses on bilateral upper extremities which he attributed to the recent fall. He also had bilateral lower extremity pitting edema which he says is stable since stopping furosemide. His abdomen was tender to palpation in the epigastric region with no rebound or guarding.

A bedside ultrasound was performed to evaluate for the source of abdominal pain.

Figure 1. Hepatorenal Junction

Figure 2. Splenorenal Junction

Figure 3. Multi-cystic liver parenchyma

Discussion:

Blood cultures grew out pseudomonas aeriginosa.  Patients with PKD can get septic from infected cysts however the source of his infection was not clear.

Polycystic kidney disease (PKD) is the most common inherited cause of end stage renal disease (ESRD) with the most common form, Autosomal Dominant PKD (ADPKD) affecting around 500,000 people in the United States and between 1 in 400 to 1 in 1000 births1. ADPKD is a progressive, multisystem disease associated with extrarenal manifestations of disease most associated with cysts in other organs such as the liver, seminal vesicle, and pancreas though connective tissue disorders including mitral valve prolapse, intracranial aneurysms, and abdominal hernias are also commonly reported2. Transplant of kidney is usually more successful after nephrectomy of native kidneys, with 1 year survival >90% and median survival of 18.7 years.

Polycystic liver disease (PLD), the most common extrarenal manifestation of PKD, is characterized by the presence of cysts in greater than 50 percent of the liver3. Between 75 and 90 percent of patients with ADPKD have associate PLD4. Notably, there is an inherited form of PLD, which is distinct from PKD but it is less common than PKD and is rarely associated with concurrent renal cysts 5.

The presence of innumerable hepatic cysts, as demonstrated in this case, provides a valuable sonographic teaching example for learners. It is critical to recognize that while renal disease is the primary driver of morbidity and mortality in ADPKD, extrarenal manifestations such as polycystic liver disease, intracranial aneurysms, and cardiac valvular disease are important contributors to patient outcomes and should be monitored and included as part of the differential diagnoses when these patients present to the emergency department. 

References:

  1. Mahboob M, Rout P, Leslie SW, Bokhari SR. Autosomal Dominant Polycystic Kidney Disease. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. Updated March 20, 2024. Available from: NCBI Bookshelf 
  2. Pirson Y. Extrarenal manifestations of autosomal dominant polycystic kidney disease. Adv Chronic Kidney Dis. 2010 Mar;17(2):173–80. doi:10.1053/j.ackd.2010.01.003 
  3. Henriques MSM, Villar EJM. Chapter 17: The Liver and Polycystic Kidney Disease. In: Li X, editor. Polycystic Kidney Disease [Internet]. Brisbane (AU): Codon Publications; Nov 2015. doi:10.15586/codon.pkd.2015.ch17 
  4. Harris PC, Torres VE. Polycystic kidney disease. Annu Rev Med. 2009;60:321–37. doi:10.1146/annurev.med.60.101707.125712 
  5. Cnossen WR, Drenth JPH. Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management. Orphanet J Rare Dis. 2014 May 1;9:69. doi:10.1186/1750-1172-9-69 
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