Julia Kelly, Cameron Smyres
A 62-year-old man who was recently diagnosed with colon cancer presents to the ED after being diagnosed with a pulmonary embolism on outside CT imaging. The patient had a CT scan of his chest for cancer staging and an incidental PE was found. He was told to seek care at the ED. The patient is asymptomatic, and specifically denies chest pain, dyspnea, acute leg swelling and otherwise feels at his baseline. He denies any recent travel and has no history of blood clots in the past.
Vitals: BP 106/70 | Pulse 55 | Temp 98 °F (36.7 °C) | Resp 19 | Wt 79.8 kg (176 lb) | SpO2 98%
Physical Exam: The patient is not in acute distress, lying in bed and breathing comfortably on room air. Lungs are clear to auscultation bilaterally. 1+ pitting edema noted in shins bilaterally. The remainder of the exam is normal.
Labs: CBC with stable chronic macrocytic anemia (Hgb 11.7). CBC, PT and PTT wnl.

ED Course: Limited bedside cardiac ultrasound showed grossly normal heart function, without pericardial effusion or right ventricular dysfunction. No evidence of right heart strain. PE team was consulted who did not recommend formal echocardiogram based on patient’s lack of symptoms, hemodynamic stability, and reassuring bedside ultrasound. Patient was started on Eliquis and referred to PE clinic for outpatient follow up.
Discussion:
Pulmonary embolism (PE) is a potentially life-threatening diagnosis that can present with a variety of symptoms, from asymptomatic to sudden hemodynamic collapse. Approximately half of PEs are diagnosed in the emergency care setting,4 making rapid identification and risk stratification especially important. Mortality can reach up to 25-50% in massive PE without prompt treatment. POCUS has been shown to be highly sensitive for large PEs and in those with abnormal vital signs.1
A rapid bedside tool, POCUS can play an important role in risk stratification of patients with PEs by evaluating for right heart strain, though data shows its utility in diagnosing PE itself might be more limited5. Pulmonary emboli block blood flow to the lungs, increasing afterload, leading to right ventricular dysfunction (RVD). RVD is an important prognostic factor and can change management. In this case, bedside echo demonstrated no evidence of right ventricular dysfunction, supporting outpatient management with apixaban and close follow-up; in contrast, evidence of right heart strain may have prompted consideration of more aggressive therapies or inpatient monitoring.
There are several sonographic findings that suggest right heart strain, including RV enlargement (RV:LV ratio), abnormal septal motion such as septal flattening (“D-sign”), and McConnell’s sign (hypokinesis of RV with apical sparing, resembling a flailing sail3). These features reflect acute pressure overload on the RV from a significant pulmonary arterial obstruction. McConnell’s sign is an indication of acute RV strain, rather than chronic changes. Acute RV strain can also be distinguished from chronic overload with the absence of RV hypertrophy.5 It is important to note that the sensitivity of POCUS for detecting right heart strain in PE is limited. For example, McConnell’s sign shows high specificity but low sensitivity for acute PE: one study finding a pool estimate of 22% sensitivity and 97% specificity.4 Additionally, absence of right heart strain on POCUS does not exclude PE, and CT PE remains the gold standard for definitive diagnosis.
In summary, while POCUS did not reveal right heart strain in this patient with confirmed PE, its use provided timely bedside evaluation of cardiac function that contributed to risk stratification and informed clinical management. This case highlights POCUS’s role as a valuable tool in the assessment of suspected PE.
References
- Alerhand S, Sundaram T, Gottlieb M. What are the echocardiographic findings of acute right ventricular strain that suggest pulmonary embolism? Anaesth Crit Care Pain Med. 2021 Apr;40(2):100852. doi: 10.1016/j.accpm.2021.100852. Epub 2021 Mar 26. PMID: 33781986.
- Daley JI, Dwyer KH, Grunwald Z, Shaw DL, Stone MB, Schick A, Vrablik M, Kennedy Hall M, Hall J, Liteplo AS, Haney RM, Hun N, Liu R, Moore CL. Increased Sensitivity of Focused Cardiac Ultrasound for Pulmonary Embolism in Emergency Department Patients With Abnormal Vital Signs. Acad Emerg Med. 2019 Nov;26(11):1211-1220. doi: 10.1111/acem.13774. Epub 2019 Sep 27. PMID: 31562679.
- Day J BA RDCS. Right Heart Evaluation | Point-of-Care Ultrasound Certification Academy [Internet]. Point-of-Care Ultrasound Certification Academy. 2023. Available from: https://www.pocus.org/right-heart-evaluation/
- Fields JM, Davis J, Girson L, Au A, Potts J, Morgan CJ, Vetter I, Riesenberg LA. Transthoracic Echocardiography for Diagnosing Pulmonary Embolism: A Systematic Review and Meta-Analysis. J Am Soc Echocardiogr. 2017 Jul;30(7):714-723.e4. doi: 10.1016/j.echo.2017.03.004. Epub 2017 May 9. PMID: 28495379.
- Rudski LG, Wyman WL, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Schiller NB. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. J Am Soc Echocardio. 2010;23(7):685-713.




















